| What does the future hold for cell-based tolerogenic therapy? | |
| | |
MedLine Citation:
|
PMID: 17653127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Evidence from animal models has shown that the transfer of regulatory T cells or tolerogenic dendritic cells can prevent or cure transplant rejection or re-establish self-tolerance in autoimmune disease. The potential of these tolerogenic cells for the treatment of T-cell-mediated diseases in humans has gained momentum in recent years. Here, Nature Reviews Immunology asks four leading researchers to provide their view on the future of cell-based tolerogenic therapy and to highlight some important issues that must be considered before this form of immunotherapy can become a reality. |
| | |
Authors:
|
Jeffrey A Bluestone; Angus W Thomson; Ethan M Shevach; Howard L Weiner |
Related Documents
:
|
20038917 - Immunohistochemical study of langerhans cells in periapical lesions: correlation with i... 1717417 - Adenosine triphosphatase-positive langerhans-like cells in the epidermis of the chicken... 16225597 - Expression of haptoglobin in human keratinocytes and langerhans cells. 20045407 - Immune cell profile in invasive cholesteatomas: preliminary findings. 14698417 - Female germ cell mutagenicity of model chemicals in drosophila melanogaster: mechanisti... 8400307 - Role of calcium in the shape control of human granulocytes. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Nature reviews. Immunology Volume: 7 ISSN: 1474-1733 ISO Abbreviation: Nat. Rev. Immunol. Publication Date: 2007 Aug |
Date Detail:
|
Created Date: 2007-07-26 Completed Date: 2007-09-13 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101124169 Medline TA: Nat Rev Immunol Country: England |
Other Details:
|
Languages: eng Pagination: 650-4 Citation Subset: IM |
Affiliation:
|
Immune Tolerance Network and of the Diabetes Center at the University of California, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Autoimmune Diseases / therapy* Forecasting Humans Immune Tolerance / immunology* Immunotherapy, Adoptive / methods* T-Lymphocytes, Regulatory / immunology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans.
Next Document: Propofol exerts greater neuroprotection with disodium edetate than without it.