| What does PET imaging add to conventional staging of head and neck cancer patients? | |
| | |
MedLine Citation:
|
PMID: 17379443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To determine the value of PET scans in the staging of patients with head and neck carcinoma. METHODS AND MATERIALS: The charts of 25 patients who underwent neck dissection, computed tomography (CT) scan, and F-18-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging as part of their initial work-up for a head and neck squamous cell cancer between 2000-2003 were reviewed. All patients underwent clinical examination, triple endoscopy, and chest radiograph as part of their clinical staging, adhering to American Joint Commission for Cancer criteria. In addition to the clinical nodal (N) stage, PET findings were incorporated to determine a second type of N staging: clinical N + PET stage. The number of neck sides and nodal levels involved on CT or PET and on pathologic examination were recorded. RESULTS: The sensitivity and specificity for detection of nodal disease were similar for CT and FDG-PET. Positive and negative likelihood ratios were similar for both diagnostic tests. None of our 25 patients had unsuspected distant disease detected by PET. CONCLUSION: The addition of PET imaging did not improve diagnostic accuracy in our patients compared with CT. PET scanning did not alter clinical management in any of the patients. |
| | |
Authors:
|
Surjeet Pohar; Robert Brown; Nancy Newman; Michael Koniarczyk; Jack Hsu; David Feiglin |
Related Documents
:
|
16193313 - Pet recognition of pulmonary metastases on pet/ct imaging: impact of attenuation-correc... 19057803 - Pet/ct in cancer: methodological considerations for comparative diagnostic phase ii stu... 22470693 - Gossypiboma of the breast: imaging findings. |
Publication Detail:
|
Type: Evaluation Studies; Journal Article; Multicenter Study Date: 2007-03-26 |
Journal Detail:
|
Title: International journal of radiation oncology, biology, physics Volume: 68 ISSN: 0360-3016 ISO Abbreviation: Int. J. Radiat. Oncol. Biol. Phys. Publication Date: 2007 Jun |
Date Detail:
|
Created Date: 2007-05-14 Completed Date: 2007-06-18 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7603616 Medline TA: Int J Radiat Oncol Biol Phys Country: United States |
Other Details:
|
Languages: eng Pagination: 383-7 Citation Subset: IM |
Affiliation:
|
Department of Radiation Oncology, SUNY Upstate Medical University, Syracuse, NY, USA. poharss@evms.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Carcinoma, Squamous Cell
/
pathology*,
radiography,
radionuclide imaging* Female Fluorodeoxyglucose F18 / diagnostic use Head and Neck Neoplasms / pathology*, radiography, radionuclide imaging* Humans Male Neck Dissection Neoplasm Staging / methods, standards* Positron-Emission Tomography / methods, standards* Radiopharmaceuticals / diagnostic use Sensitivity and Specificity Tomography, X-Ray Computed / standards |
| Chemical | |
Reg. No./Substance:
|
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Assessment of gross tumor volume regression and motion changes during radiotherapy for non-small-cel...
Next Document: Fludarabine allows dose reduction for total body irradiation in pediatric hematopoietic stem cell tr...