Document Detail

What do we most need to learn about food intake regulation?
MedLine Citation:
PMID:  9688108     Owner:  NLM     Status:  MEDLINE    
Many mechanisms are known to contribute to the regulation of food intake. This notwithstanding, variations in food intake from day to day and deviations from daily energy balance are substantial and very readily tolerated. Yet, despite this very loose short-term adjustment of food intake to energy expenditure, most adults maintain stable body compositions during long periods of their lives. This is particularly puzzling when it occurs in the face of an ubiquitous supply of appealing foods and under circumstances that, in many ways, promote food consumption. Thus, the question arises as to why people in affluent societies eat substantially less on most days, than the amounts that they can so readily consume on high-intake days? In addition to conscious decisions, physiological phenomena restraining food consumption must be presumed to play an important role in limiting weight. But what are the phenomena that cause spontaneous reduction in food intake after a few days of overeating? Our ignorance about the nature and impact of these effects stands in the way of a better understanding of body weight regulation and of the factors responsible for the induction and maintenance of obesity.
J P Flatt
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Obesity research     Volume:  6     ISSN:  1071-7323     ISO Abbreviation:  Obes. Res.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-10-28     Completed Date:  1998-10-28     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9305691     Medline TA:  Obes Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  307-10     Citation Subset:  IM    
Department of Biochemistry and Molecular Biology, University of Massachusetts Medical School, Worcester 01655-0103, USA.
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MeSH Terms
Appetite Regulation*
Body Composition
Body Weight*
Obesity / physiopathology*,  psychology*
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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