Document Detail


What are we measuring with GABA magnetic resonance spectroscopy?
MedLine Citation:
PMID:  22046466     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
A number of recent papers1-3 have demonstrated a relationship between in vivo concentration of GABA, as assessed using Magnetic Resonance Spectroscopy (MRS), and an individual's task performance, giving a unique insight into the relationship between physiology and behavior. However, interpretation of the functional significance of the MRS GABA measure is not straightforward. Here we discuss some of the outstanding questions as to how total concentration of GABA within a cortical region relates to phasic and tonic GABA activity within the cortical volume studied.
Authors:
Charlotte J Stagg; Velicia Bachtiar; Heidi Johansen-Berg
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Publication Detail:
Type:  Journal Article     Date:  2011-09-01
Journal Detail:
Title:  Communicative & integrative biology     Volume:  4     ISSN:  1942-0889     ISO Abbreviation:  Commun Integr Biol     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-11-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101478473     Medline TA:  Commun Integr Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  573-5     Citation Subset:  -    
Affiliation:
Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB); Nuffield Department of Clinical Neurosciences; University of Oxford; Oxford, UK.
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