Document Detail


What can fear and reward learning teach us about depression?
MedLine Citation:
PMID:  23299804     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The precise neural substrates of major depressive disorder (MDD) remain elusive, and FDA-approved antidepressants fail at least one-third of treatment-seeking patients. It is imperative, therefore, to identify novel research strategies to tackle the factors impeding progress. In this chapter we propose that the knowledge derived from computational investigations of associative learning might offer new insights into the neurobiology of MDD.
Authors:
Katherine A Collins; Daniela Schiller
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current topics in behavioral neurosciences     Volume:  14     ISSN:  1866-3370     ISO Abbreviation:  Curr Top Behav Neurosci     Publication Date:  2013  
Date Detail:
Created Date:  2013-03-27     Completed Date:  2013-08-08     Revised Date:  2014-03-25    
Medline Journal Info:
Nlm Unique ID:  101535383     Medline TA:  Curr Top Behav Neurosci     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  223-42     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Association Learning / physiology*
Depressive Disorder, Major / physiopathology*,  psychology*
Fear / psychology*
Humans
Reward*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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