Document Detail


Western blot analysis as an aid for the diagnosis of cutaneous leishmaniasis due to Leishmania major.
MedLine Citation:
PMID:  22657532     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Cutaneous leishmaniasis (CL) due to Leishmania major is endemic in the Old World. To evaluate the diagnostic value of Western blot (WB) compared with IFAT, we tested serum samples from 45 patients with proven CL. Twenty-one (47%) patients were positive by IFAT and all patients were positive by WB with specific bands against 14kDa and/or 18kDa Leishmania antigens. Our results suggest that WB could be a useful non-invasive tool for the diagnosis of CL caused by L. major.
Authors:
Christelle Pomares; Laura Despierres; Pascal Del Giudice; Pascal Delaunay; Grégory Michel; Bernard Ferrua; Pierre Marty
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-30
Journal Detail:
Title:  Transactions of the Royal Society of Tropical Medicine and Hygiene     Volume:  -     ISSN:  1878-3503     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-6-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7506129     Medline TA:  Trans R Soc Trop Med Hyg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Faculté de Médecine, Université de Nice-Sophia Antipolis, Service de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Nice, Nice, France; Bâtiment Universitaire Archimed, INSERM U895, C3M, Equipe 6, 151 Route St Antoine de Ginestière, BP 23194, 06204 Nice Cedex 3, France.
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