Document Detail


West Nile virus infection and immunity.
MedLine Citation:
PMID:  23321534     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
West Nile virus (WNV) is an emerging neurotropic flavivirus that is transmitted to humans through the bite of an infected mosquito. WNV has disseminated broadly in the Western hemisphere and now poses a significant public health risk. The continuing spread of WNV, combined with the lack of specific therapeutics or vaccines to combat or prevent infection, imparts a pressing need to identify the viral and host processes that control the outcome of and immunity to WNV infection. Here, we provide an overview of recent research that has revealed the virus-host interface controlling WNV infection and immunity.
Authors:
Mehul S Suthar; Michael S Diamond; Michael Gale
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nature reviews. Microbiology     Volume:  11     ISSN:  1740-1534     ISO Abbreviation:  Nat. Rev. Microbiol.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101190261     Medline TA:  Nat Rev Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  115-28     Citation Subset:  IM    
Affiliation:
1] Department of Immunology, University of Washington, School of Medicine, 1959 NE Pacific Street, Seattle, Washington 98195, USA. [2] Department of Pediatrics and Children's Healthcare of Atlanta, Emory Vaccine Center, Emory University, Atlanta, Georgia 30329, USA.
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