Document Detail

Wernicke's encephalopathy complicating pregnancy in a woman with neonatal necrotizing enterocolitis and resultant chronic malabsorption.
MedLine Citation:
PMID:  19288394     Owner:  NLM     Status:  MEDLINE    
Wernicke's encephalopathy (WE) is a metabolic disturbance resulting from severe thiamine deficiency classically described in malnourished alcoholics. Untreated, it can result in stupor, coma, and death. WE has previously been reported as a complication of pregnancy in women with hyperemesis gravidarum. We report a case of WE complicating pregnancy in a woman with chronic malabsorption secondary to premature birth and subsequent necrotizing enterocolitis (NEC). Our patient progressed through classic stages of WE before lapsing into a coma. She made a complete recovery after aggressive intravenous thiamine and nutritional support. This is the first report of WE in pregnancy secondary to NEC-related chronic malabsorption. We report this case to bring attention to a potential pregnancy complication affecting women with malabsorptive conditions.
Ned L Williams; Samantha Wiegand; David S McKenna
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-03-13
Journal Detail:
Title:  American journal of perinatology     Volume:  26     ISSN:  1098-8785     ISO Abbreviation:  Am J Perinatol     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-20     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  519-21     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Wright State University, Dayton, Ohio, USA.
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MeSH Terms
Cesarean Section
Combined Modality Therapy
Emergency Treatment
Enterocolitis, Necrotizing / complications,  diagnosis*,  surgery
Follow-Up Studies
Gestational Age
HELLP Syndrome / diagnosis*,  therapy
Infant, Newborn
Infant, Premature*
Malabsorption Syndromes / complications,  diagnosis*,  therapy
Pregnancy Complications / diagnosis,  therapy
Rare Diseases
Risk Assessment
Treatment Outcome
Wernicke Encephalopathy / diagnosis*,  etiology,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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