Document Detail


Wernicke-Korsakoff encephalopathy.
MedLine Citation:
PMID:  17934284     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Wernicke described the clinical features of three patients, including two alcoholics, suffering from confusion, ataxia and ophthalmoplegia in whom pathologically he found 'polioencephalitis haemorrhagica superioris'. Korsakoff's doctoral thesis related similar findings but expanded the confabulation and amnesic elements, relating them to alcoholism. This paper, which summarises the salient aspects of the syndrome, discusses their work and shows important earlier descriptions by James Jackson, (1822) Samuel Wilks (1868) and Charles Gayet (1875).
Authors:
J M S Pearce
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Publication Detail:
Type:  Biography; Historical Article; Journal Article     Date:  2007-10-11
Journal Detail:
Title:  European neurology     Volume:  59     ISSN:  1421-9913     ISO Abbreviation:  Eur. Neurol.     Publication Date:  2008  
Date Detail:
Created Date:  2007-12-18     Completed Date:  2008-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0150760     Medline TA:  Eur Neurol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  101-4     Citation Subset:  IM    
Copyright Information:
(c) 2007 S. Karger AG, Basel
Affiliation:
Emeritus Consultant Neurologist, Department of Neurology, Hull Royal Infirmary and Hull York Medical School, Hull, UK.
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MeSH Terms
Descriptor/Qualifier:
Alcohol Amnestic Disorder / diagnosis,  history*,  physiopathology
History, 19th Century
History, 20th Century
Humans
Male
Middle Aged
Prognosis
Thiamine Deficiency
Wernicke Encephalopathy / diagnosis,  history*,  physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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