| Wells Syndrome with Multiorgan Involvement Mimicking Hypereosinophilic Syndrome. | |
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MedLine Citation:
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PMID: 20652113 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Eosinophil-associated diseases represent a spectrum of heterogeneous disorders, where blood and cutaneous eosinophilia is the most important feature and eosinophils are the principal cause of cutaneous lesions. These diseases show some similarities in the clinical features but also many distinctive characteristics [Saurat et al., Dermatologia e malattie sessualmente trasmesse, Milano, Masson, 2000]. Wells syndrome is one of these disorders and is an uncommon recurrent inflammatory dermatosis, rarely associated to signs and symptoms of multiple organ involvement [Arch Dermatol 2006;142:1157-1161]. Hypereosinophilic syndrome, in contrast, constitutes a group of idiopathic disorders characterized by blood eosinophilia for at least 6 months, associated with single or multiple organ system dysfunction [Arch Dermatol 2006;142:1157-1161]. Clinically atypical Wells syndrome with multiorgan involvement is reported here. A correct diagnosis is difficult in this case, but clinical and histopathological features are compatible with this diagnosis. The reported condition likely represents a borderline hypereosinophilic disease, in which clinical features of both hypereosinophilic syndrome and Wells syndrome are present. |
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Authors:
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M Carlesimo; L Fidanza; E Mari; G Feliziani; A Narcisi; G De Marco; A Bartolazzi; G Camplone |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2009-9-12 |
Journal Detail:
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Title: Case reports in dermatology Volume: 1 ISSN: 1662-6567 ISO Abbreviation: - Publication Date: 2009 |
Date Detail:
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Created Date: 2010-7-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101517685 Medline TA: Case Rep Dermatol Country: - |
Other Details:
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Languages: ENG Pagination: 44-48 Citation Subset: - |
Affiliation:
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U.O.C. Dermatology, II Unit University of Rome 'Sapienza', Rome, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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