Document Detail


Well-differentiated liposarcoma/atypical lipomatous tumor of the oral cavity: report of three cases and review of the literature.
MedLine Citation:
PMID:  22234501     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Atypical Lipomatous Tumor/Well Differentiated Liposarcoma (ALT/WDLS) is a soft tissue sarcoma of intermediate malignant behavior, most frequently affecting the retroperitoneum and lower extremities. Oral liposarcomas are very rare neoplasms, the most common histological subtype being ALT/WDLS. In this study, three additional cases of ALT/WDLS located on the tongue (2 cases) and the lower lip (1 case), respectively, are described. Analysis of the salient clinicopathologic features of 63 oral ALT/WDLS cases previously reported in the English language literature, as well as of the 3 cases presented in this study, indicates that the indolent biologic behavior of this tumor justifies its designation as a locally spreading malignant neoplasm, affording a rather conservative surgical approach.
Authors:
Evangelia Piperi; Konstantinos I Tosios; Nikolaos G Nikitakis; Vasileios F Kyriakopoulos; Fotios Tzerbos; Ioannis G Koutlas; Alexandra Sklavounou
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2012-01-11
Journal Detail:
Title:  Head and neck pathology     Volume:  6     ISSN:  1936-0568     ISO Abbreviation:  Head Neck Pathol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-20     Completed Date:  2012-12-31     Revised Date:  2013-06-26    
Medline Journal Info:
Nlm Unique ID:  101304010     Medline TA:  Head Neck Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  354-63     Citation Subset:  IM    
Affiliation:
Department of Oral Pathology and Medicine, Dental School, University of Athens, 2 Thivon Street, 11527, Athens, Greece. liapiperi@dent.uoa.gr
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MeSH Terms
Descriptor/Qualifier:
Adult
Cell Differentiation*
Female
Humans
Liposarcoma / pathology*,  surgery
Middle Aged
Mouth Neoplasms / pathology*,  surgery
Comments/Corrections

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