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Weight gain regardless of pre-pregnancy BMI and fetal gender affect the response to labor induction in postdate pregnancy.
MedLine Citation:
PMID:  23339607     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract Objective: To evaluate whether maternal weight and BMI and their increase throughout pregnancy are associated with the response to labor induction in postdate pregnancies. Methods: A total of 376 nulliparous women carrying singleton postdate pregnancies with unfavorable cervix were enrolled. We considered as primary outcome vaginal delivery within 24 hours after induction, and outcomes were divided into responders (n = 258) and non-responders (n = 107) to the induction of labor to perform the statistical analyses. Results: In the total population of study, women who successfully delivered within 24 hours differed significantly from the remaining patients in terms of maternal weight gain (P = 0.009) and BMI increase (P = 0.02) during pregnancy. In addition, males were significantly more numerous (P = 0.005) than females among newborns of women no responding to induction of labor. In the multivariate analysis, maternal weight gain and fetal sex influenced significantly the induction response. The occurrence of a failed induction of labor was more likely in patients presenting a greater maternal weight gain (cut-off 12 kg) and male fetus. Conclusions: Weight gain over 12 Kg regardless of pre-pregnancy weight and male fetal gender are two novel potential risk factors for the prediction of failure to induction of labor in postdate pregnancy.
Authors:
Michela Torricelli; Chiara Voltolini; Nathalie Conti; Caterina Bocchi; Filiberto M Severi; Felice Petraglia
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-22
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Obstetrics and Gynecology, Department of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
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