Document Detail

Weight estimation by three-dimensional ultrasound imaging in the small fetus.
MedLine Citation:
PMID:  18663765     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To improve birth weight estimation in fetuses weighing <or= 1600 g at birth by deriving a new formula including measurements obtained using three-dimensional (3D) sonography. METHODS: In a prospective cohort study, biometric data of 150 singleton fetuses weighing <or= 1600 g at birth were obtained by sonographic examination within 1 week before delivery. Exclusion criteria were multiple pregnancy, intrauterine death as well as major structural or chromosomal anomalies. A new formula was derived using our data, and was then compared with currently available equations for estimating weight in the preterm fetus. RESULTS: Different statistical estimation strategies were pursued. Gradient boosting with component- wise smoothing splines achieved the best results. The resulting new formula (estimated fetal weight = 656.41 + 1.8321 x volABDO + 31.1981 x HC + 5.7787 x volFEM + 73.5214 x FL + 8.3009 x AC - 449.8863 x BPD + 32.5340 x BPD(2), where volABDO is abdominal volume determined by 3D volumetry, HC is head circumference, volFEM is thigh volume determined by 3D volumetry, FL is femur length and BPD is biparietal diameter) proved to be superior to established equations in terms of mean squared prediction errors, signed percentage errors and absolute percentage errors. CONCLUSIONS: Our new formula is relatively easy to use and needs no adjustment to weight percentiles or to fetal lie. In fetuses weighing <or= 1600 g at birth it is superior to weight estimation by traditional formulae using two-dimensional measurements.
R L Schild; M Maringa; J Siemer; B Meurer; N Hart; T W Goecke; M Schmid; T Hothorn; M E Hansmann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  32     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-04     Completed Date:  2009-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  168-75     Citation Subset:  IM    
Copyright Information:
(c) 2008 ISUOG. Published by John Wiley & Sons, Ltd.
Department of Obstetrics and Gynecology, University Women's Hospital, Erlangen, Germany.
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MeSH Terms
Anthropometry / methods*
Biometry / methods*
Birth Weight*
Echocardiography, Three-Dimensional / methods*
Fetal Weight*
Gestational Age
Infant, Newborn
Infant, Small for Gestational Age
Pregnancy Trimester, Third
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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