Document Detail

Weight-bearing compared with non-weight-bearing following osteochondral autograft transfer for small defects in weight-bearing areas in the femoral articular cartilage of the knee.
MedLine Citation:
PMID:  25143504     Owner:  NLM     Status:  In-Data-Review    
BACKGROUND: Patients are routinely kept non-weight-bearing for four to eight weeks following osteochondral autograft transfer to repair cartilage defects of the medial and/or lateral femoral condyle. Therefore, the objective of this novel study was to investigate whether postoperative weight-bearing restrictions affect the outcomes of cartilage repair when an osteochondral autograft transfer system is used to repair small defects in weight-bearing areas of femoral articular cartilage.
METHODS: This a retrospective comparative study. Following review of the charts on 567 consecutive arthroscopic osteochondral autograft transfers, three homogeneous groups of patients with consecutive cases were identified: group A, cases of patients who were non-weight-bearing following the procedure (n = 68); group B, cases of those who were non-weight-bearing following the procedure with concomitant anterior cruciate ligament reconstruction (n = 29); and group C, cases of those who were weight-bearing as tolerated following the procedure (n = 437). The cases of patients whose knees underwent second-look (repeat) arthroscopy were stratified into two subgroups: non-weight-bearing (n = 20) and weight-bearing as tolerated (n = 42). Graft position and manifestation of a repair-adjacent defect (Outerbridge grade-III or IV cartilage defect that develops adjacent to the original osteochondral autograft transfer repair) were assessed during second-look arthroscopy. Cartilage repair was retrospectively assessed from second-look arthroscopy pictures by a blinded, independent orthopaedic surgeon with use of the International Cartilage Repair Society macroscopic cartilage-repair assessment tool. Postoperative complication rates were compared among the three primary groups.
RESULTS: The mean grafted area was 0.72 cm(2) (range, 0.16 to 1.45 cm(2)) and 0.73 cm(2) (range, 0.16 to 1.80 cm(2)) for the non-weight-bearing and weight-bearing-as-tolerated second-look subgroups, respectively. The mean International Cartilage Repair Society score was 11.12 and 11.25 points (near-normal cartilage) for the non-weight-bearing and weight-bearing-as-tolerated subgroups (p = 0.71) at a mean follow-up of 42.7 and 33.0 months, respectively. There was no significant difference in the duration of follow-up (p = 0.58), repair-adjacent defect prevalence (p = 0.94), or graft position (p = 0.99) between the two subgroups. Weight-bearing-as-tolerated patients (group C) experienced significantly fewer deep vein thrombosis and arthrofibrosis complications compared with non-weight-bearing patients (groups A and B) (p < 0.001).
CONCLUSIONS: Postoperative weight-bearing restrictions did not affect mid-term cartilage repair outcomes in patients who underwent second-look arthroscopy when an osteochondral autograft transfer system was used to repair small defects in weight-bearing areas of cartilage of the medial and/or lateral femoral condyle.
LEVEL OF EVIDENCE: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
James R Kosiur; Robert A Collins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of bone and joint surgery. American volume     Volume:  96     ISSN:  1535-1386     ISO Abbreviation:  J Bone Joint Surg Am     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-08-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0014030     Medline TA:  J Bone Joint Surg Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e136     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2014 by The Journal of Bone and Joint Surgery, Incorporated.
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