| Weight and mortality following heart failure hospitalization among diabetic patients. | |
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MedLine Citation:
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PMID: 21854892 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Type 2 diabetes is an important risk factor for heart failure and is common among patients with heart failure. The impact of weight on prognosis after hospitalization for acute heart failure among patients with diabetes is unknown. The objective of this study was to examine all-cause mortality in relation to weight status among patients with type 2 diabetes hospitalized for decompensated heart failure. METHODS: The Worcester Heart Failure Study included adults admitted with acute heart failure to all metropolitan Worcester medical centers in 1995 and 2000. The weight status of 1644 patients with diabetes (history of type 2 diabetes in medical record or admission serum glucose ≥200 mg/dL) was categorized using body mass index calculated from height and weight at admission. Survival status was ascertained at 1 and 5 years after hospital admission. RESULTS: Sixty-five percent of patients were overweight or obese and 3% were underweight. Underweight patients had 50% higher odds of all-cause mortality within 5 years of hospitalization for acute heart failure than normal weight patients. Class I and II obesity were associated with 20% and 40% lower odds of dying. Overweight and Class III obesity were not associated with mortality. Results were similar for mortality within 1 year of hospitalization for acute heart failure. CONCLUSIONS: The mechanisms underlying the association between weight status and mortality are not fully understood. Additional research is needed to explore the effects of body composition, recent weight changes, and prognosis after hospitalization for heart failure among patients with diabetes. |
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Authors:
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Molly E Waring; Jane S Saczynski; David McManus; Michael Zacharias; Darleen Lessard; Joel M Gore; Robert J Goldberg |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: The American journal of medicine Volume: 124 ISSN: 1555-7162 ISO Abbreviation: Am. J. Med. Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-08-22 Completed Date: 2011-10-24 Revised Date: 2012-04-13 |
Medline Journal Info:
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Nlm Unique ID: 0267200 Medline TA: Am J Med Country: United States |
Other Details:
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Languages: eng Pagination: 834-40 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Epidemiology of Chronic Diseases and Vulnerable Populations, Department of Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA 01655, USA. molly.waring@umassmed.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Aged, 80 and over Body Weight* Cause of Death Diabetes Complications / mortality* Diabetes Mellitus, Type 2 / mortality* Female Heart Failure / mortality* Hospitalization / statistics & numerical data* Humans Male Massachusetts Middle Aged Obesity / mortality Odds Ratio Overweight / mortality Prognosis Proportional Hazards Models Risk Factors Survival Analysis Thinness / mortality |
| Grant Support | |
ID/Acronym/Agency:
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1U01HL105268-01/HL/NHLBI NIH HHS; R37 HL069874-10/HL/NHLBI NIH HHS; R37 HL69874/HL/NHLBI NIH HHS; UL1 RR031982-02/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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