Document Detail

Wegener's granulomatosis in pregnancy: a novel approach to management.
MedLine Citation:
PMID:  15384037     Owner:  NLM     Status:  MEDLINE    
Wegener's granulomatosis rarely is diagnosed in women of childbearing age and is, thus, uncommonly encountered in pregnancy. Although conventional treatment with steroids and cyclophosphamide controls disease activity in 90% of patients, the associated teratogenicity of such a regimen warrants careful consideration in pregnancy. We describe successful remission induction with the use of intravenous immunoglobulin and steroids alone in a woman diagnosed with de novo Wegener's granulomatosis during the first trimester of pregnancy.
Rosemary Masterson; Rebecca Pellicano; Karl Bleasel; Lawrence P McMahon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  44     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-22     Completed Date:  2005-03-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e68-72     Citation Subset:  IM    
Department of Nephrology, Royal Melbourne Hospital, Parkville, Melbourne, Victoria, Australia.
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MeSH Terms
Glucocorticoids / therapeutic use*
Immunoglobulins, Intravenous / therapeutic use*
Prednisolone / therapeutic use*
Pregnancy Complications / drug therapy*
Pregnancy Trimester, First
Remission Induction
Wegener Granulomatosis / drug therapy*
Reg. No./Substance:
0/Glucocorticoids; 0/Immunoglobulins, Intravenous; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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