| Weekly doxorubicin chemotherapy for breast cancer in pregnancy. A case report. | |
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MedLine Citation:
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PMID: 1494809 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The simultaneous occurrence of breast cancer and pregnancy is rare. Little data are available about cytostatic treatment in patients with breast cancer during pregnancy. We report on a 31-year-old woman with a 28-week pregnancy and a T3 N+ Mx breast cancer treated with weekly doxorubicin chemotherapy. This was a well tolerated treatment without toxicity or complications for the mother. A partial response of the tumor was observed after 4 treatment courses. A normal baby was delivered. Doxorubicin and its metabolites were not detected in amniotic fluid collected through amniocentesis. Macroscopic and pathologic examinations of the placenta were normal. Although larger experiences are needed, weekly doxorubicin seems to yield satisfactory results without additional risks of fetal distress or malformations when given in women during the second and third trimester of pregnancy. |
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Authors:
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S Barni; A Ardizzoia; G Zanetta; E Strocchi; P Lissoni; G Tancini |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Tumori Volume: 78 ISSN: 0300-8916 ISO Abbreviation: Tumori Publication Date: 1992 Oct |
Date Detail:
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Created Date: 1993-03-10 Completed Date: 1993-03-10 Revised Date: 2008-12-12 |
Medline Journal Info:
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Nlm Unique ID: 0111356 Medline TA: Tumori Country: ITALY |
Other Details:
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Languages: eng Pagination: 349-50 Citation Subset: IM |
Affiliation:
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Department of Oncologic Radiotherapy, S. Gerardo Hospital, Monza, Milano, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Breast Neoplasms / drug therapy* Doxorubicin / therapeutic use* Drug Administration Schedule Female Humans Pregnancy Pregnancy Complications, Neoplastic / drug therapy* |
| Chemical | |
Reg. No./Substance:
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23214-92-8/Doxorubicin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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