Document Detail

Weber-Christian disease associated with multiple perforations of the ileum and colon.
MedLine Citation:
PMID:  2741893     Owner:  NLM     Status:  MEDLINE    
Panperitonitis developed in a 57-yr-old Japanese man during the course of Weber-Christian disease (WCD). Emergent operation disclosed three perforations of the ascending colon and two of the distal ileum. Histological study of the surgical specimen showed that all perforations were located at the centers of acute subserosal panniculitic foci. No vasculitis was discerned. In the previously reported three cases of WCD with intestinal perforation, perforation was solitary and seen in the small intestine. The cause of perforation was considered to be vasculitis in two cases. In the remaining one, panniculitis around the perforation was in chronic granulomatous stage. This was the first case of WCD in which acute subserosal panniculitis caused multiple ileocolonic perforations.
H Kiguchi; K Kasahara; M Mochizuki; Y Yasuda; T Ishibashi; F Konishi; K Kanazawa; K Saitoh; K Waza; H Kawamura
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  84     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-08-02     Completed Date:  1989-08-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  808-10     Citation Subset:  IM    
Department of Surgery, Jichi Medical School, Tochigi, Japan.
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MeSH Terms
Acute Disease
Colonic Diseases / etiology*,  pathology
Ileal Diseases / etiology*,  pathology
Intestinal Perforation / etiology*,  pathology
Middle Aged
Panniculitis, Nodular Nonsuppurative / complications*,  pathology
Vasculitis / etiology

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