| Weather-related changes in 24-hour blood pressure profile: effects of age and implications for hypertension management. | |
| | |
MedLine Citation:
|
PMID: 16380524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A downward titration of antihypertensive drug regimens in summertime is often performed on the basis of seasonal variations of clinic blood pressure (BP). However, little is known about the actual interaction between outdoor air temperature and the effects of antihypertensive treatment on ambulatory BP. The combined effects of aging, treatment, and daily mean temperature on clinic and ambulatory BP were investigated in 6404 subjects referred to our units between October 1999 and December 2003. Office and mean 24-hour systolic BP, as well as morning pressure surge, were significantly lower in hot (>90th percentiles of air temperature; 136+/-19, 130+/-14, and 33.3+/-16.1 mm Hg; P<0.05 for all), and higher in cold (<10th percentiles) days (141+/-12, 133+/-11, and 37.3+/-9.5 mm Hg; at least P<0.05 for all) when compared with intermediate days (138+/-18, 132+/-14, and 35.3+/-15.4 mm Hg). At regression analysis, 24-hour and daytime systolic pressure were inversely related to temperature (P<0.01 for all). Conversely, nighttime systolic pressure was positively related to temperature (P<0.02), with hot days being associated with higher nighttime pressure. Air temperature was identified as an independent predictor of nighttime systolic pressure increase in the group of elderly treated hypertensive subjects only. No significant relationship was found between air temperature and heart rate. Our results show for the first time that hot weather is associated with an increase in systolic pressure at night in treated elderly hypertensive subjects. This may be because of a nocturnal BP escape from the effects of a lighter summertime drug regimen and may have important implications for seasonal modulation of antihypertensive treatment. |
| | |
Authors:
|
Pietro Amedeo Modesti; Marco Morabito; Iacopo Bertolozzi; Luciano Massetti; Gabriele Panci; Camilla Lumachi; Alessia Giglio; Grzegorz Bilo; Gianluca Caldara; Laura Lonati; Simone Orlandini; Giampiero Maracchi; Giuseppe Mancia; Gian Franco Gensini; Gianfranco Parati |
Related Documents
:
|
9298044 - Comparison of manual versus automated blood pressure measurements in treated hypertensi... 20339354 - Method of mean value calculation as an additional source of variability in ambulatory b... 15249794 - Comprehensive lifestyle modification and blood pressure control: a review of the premie... 16407684 - Characteristics and management of patients presenting to the emergency department with ... 19505274 - Diuretics: still essential drugs for the management of hypertension. 3907484 - Potassium supplementation fails to lower blood pressure in hypertensive patients receiv... |
Publication Detail:
|
Type: Journal Article Date: 2005-12-27 |
Journal Detail:
|
Title: Hypertension Volume: 47 ISSN: 1524-4563 ISO Abbreviation: Hypertension Publication Date: 2006 Feb |
Date Detail:
|
Created Date: 2006-01-25 Completed Date: 2006-02-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7906255 Medline TA: Hypertension Country: United States |
Other Details:
|
Languages: eng Pagination: 155-61 Citation Subset: IM |
Affiliation:
|
Clinica Medica Generale e Cardiologia, University of Florence, Florence, Italy. pamodesti@unifi.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aging* Antihypertensive Agents / therapeutic use* Blood Pressure* Blood Pressure Monitoring, Ambulatory Circadian Rhythm* Climate Cross-Sectional Studies Heart Rate Humans Hypertension / drug therapy*, epidemiology, physiopathology* Middle Aged Prevalence Temperature Weather* |
| Chemical | |
Reg. No./Substance:
|
0/Antihypertensive Agents |
| Comments/Corrections | |
Comment In:
|
Hypertension. 2006 Feb;47(2):139-40
[PMID:
16380525
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Aortic pulse wave velocity is associated with the presence and quantity of coronary artery calcium: ...
Next Document: Retinal vessel diameters and risk of hypertension: the Rotterdam Study.