Document Detail

Wavelet processing of systolic murmurs to assist with clinical diagnosis of heart disease.
MedLine Citation:
PMID:  12923978     Owner:  NLM     Status:  MEDLINE    
Despite advances in imaging technologies for the heart, screening of patients for cardiac pathology continues to include the use of traditional stethoscope auscultation. Detection of heart murmurs by the primary care physician often results in the ordering of additional expensive testing or referral to cardiology subspecialists, although many of the patients are eventually found to have no pathologic condition. In contrast, auscultation by an experienced cardiologist is highly sensitive and specific for detecting heart disease. Although attempts have been made to automate screening by auscultation, no device is currently available to fulfill this function. Multiple indicators of pathology are nonetheless available from heart sounds and can be elicited using certain signal processing techniques such as wavelet analysis. Results presented here show that a signal of pathology, the systolic murmur, can reliably be detected and classified as pathologic using a portable electrocardiogram and heart sound measurement unit combined with a wavelet-based algorithm. Wavelet decomposition holds promise for extending these results to detection and evaluation of other audible pathologic indicators.
C Scott Hayek; W Reid Thompson; Charles Tuchinda; Richard A Wojcik; Joseph S Lombardo
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article; Validation Studies    
Journal Detail:
Title:  Biomedical instrumentation & technology / Association for the Advancement of Medical Instrumentation     Volume:  37     ISSN:  0899-8205     ISO Abbreviation:  Biomed Instrum Technol     Publication Date:    2003 Jul-Aug
Date Detail:
Created Date:  2003-08-19     Completed Date:  2004-04-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8905560     Medline TA:  Biomed Instrum Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  263-70     Citation Subset:  IM    
Johns Hopkins Applied Physics Laboratory, 11100 Johns Hopkins Road, Laurel, MD 20723-6099, USA.
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MeSH Terms
Databases, Factual
Diagnosis, Computer-Assisted / methods*
Heart Diseases / diagnosis
Heart Murmurs / diagnosis*
Phonocardiography / instrumentation,  methods*
Reference Values
Reproducibility of Results
Sensitivity and Specificity
Signal Processing, Computer-Assisted*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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