Document Detail


Wavelet bidomain sample entropy analysis to predict spontaneous termination of atrial fibrillation.
MedLine Citation:
PMID:  18175860     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ability to predict if an atrial fibrillation (AF) episode terminates spontaneously or not through non-invasive techniques is a challenging problem of great clinical interest. This fact could avoid useless therapeutic interventions and minimize the risks for the patient. The present work introduces a robust AF prediction methodology carried out by estimating, through sample entropy (SampEn), the atrial activity (AA) organization increase prior to AF termination from the surface electrocardiogram (ECG). This regularity variation appears as a consequence of the decrease in the number of reentries wandering throughout the atrial tissue. AA was obtained from surface ECG recordings by applying a QRST cancellation technique. Next, a robust and reliable classification process for terminating and non-terminating AF episodes was developed, making use of two different wavelet decomposition strategies. Finally, the AA organization both in time and wavelet domains (bidomain) was estimated via SampEn. The methodology was validated using a training set consisting of 20 AF recordings with known termination properties and a test set of 30 recordings. All the training signals and 93.33% of the test set were correctly classified into terminating and sustained AF, obtaining 93.75% sensitivity and 92.86% specificity. It can be concluded that spontaneous AF termination can be reliably and noninvasively predicted by applying wavelet bidomain sample entropy.
Authors:
Raúl Alcaraz; José Joaquín Rieta
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-01-03
Journal Detail:
Title:  Physiological measurement     Volume:  29     ISSN:  0967-3334     ISO Abbreviation:  Physiol Meas     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-07     Completed Date:  2008-04-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306921     Medline TA:  Physiol Meas     Country:  England    
Other Details:
Languages:  eng     Pagination:  65-80     Citation Subset:  IM    
Affiliation:
Innovation in Bioengineering Research Group, University of Castilla-La Mancha, Campus Universitario, 16071 Cuenca, Spain. raul.alcaraz@uclm.es
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MeSH Terms
Descriptor/Qualifier:
Algorithms
Atrial Fibrillation / diagnosis*,  physiopathology
Electrocardiography / methods*
Humans
Models, Statistical
Probability
ROC Curve
Sensitivity and Specificity
Signal Processing, Computer-Assisted*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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