Document Detail

Wave similarity of human ventricular fibrillation from bipolar electrograms.
MedLine Citation:
PMID:  17224416     Owner:  NLM     Status:  MEDLINE    
AIMS: The aim of this report was to review existing techniques for assessment of directionality in fibrillation and to describe the concept of wave similarity analysis in human VF. METHODS: We applied a technique called wave similarity analysis to bipolar electrograms to study directionality during various rhythms (sinus rhythm, ventricular tachycardia and ventricular fibrillation) in humans. This technique uses the barycentre to determine the activation time and a similarity index is calculated using a technique described previously for AF studies. RESULTS: We show here that using the wave similarity concept it is possible to recognize myocardial regions that are activated from multiple directions and differentiate those areas from regions that are activated by wave fronts in similar direction or at the exact mirror angle in ventricular fibrillation. CONCLUSIONS: Wave similarity analysis provides a tool for assessing directional organization in human VF. This analysis of directional organization may have implications for the study of mechanisms of VF in the clinical arena.
Stephane Masse; Eugene Downar; Vijay Chauhan; Elias Sevaptsidis; Kumaraswamy Nanthakumar
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  9     ISSN:  1099-5129     ISO Abbreviation:  Europace     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-16     Completed Date:  2007-03-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  10-9     Citation Subset:  IM    
University of Toronto, Toronto, Ontario, Canada.
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MeSH Terms
Electrocardiography / methods,  statistics & numerical data*
Electrophysiologic Techniques, Cardiac / methods
Heart / physiology
Models, Theoretical
Tachycardia, Ventricular / physiopathology
Ventricular Fibrillation / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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