Document Detail

Watershed infarcts in a multiple microembolic model of monkey.
MedLine Citation:
PMID:  21640789     Owner:  NLM     Status:  Publisher    
It has long been debated whether watershed infarcts are caused by hemodynamic or embolic mechanisms. In the present study, we investigated microembolic roles in the pathogenesis of watershed infarcts by examining MRI in a macaque monkey model of multiple microinfarcts. 50μm microbeads were injected into each internal carotid artery twice with a month interval. Monkeys (n=4) injected with 2250-2800 microbeads per unilateral side showed both cortical and internal watershed infarcts in the acute phase and atrophic changes with microbleeds in the chronic phase. These results suggest embolic pathogenesis can contribute to the genesis of both cortical and internal watershed infarcts in primates.
Takakuni Maki; Hideaki Wakita; Mitsuhito Mase; Iori Itagaki; Naoyuki Saito; Fumiko Ono; Kayo Adachi; Hidefumi Ito; Ryosuke Takahashi; Masafumi Ihara; Hidekazu Tomimoto
Related Documents :
24043299 - C-reactive protein, but not low-density lipoprotein cholesterol levels, associate with ...
23945449 - Positive affect and survival in patients with stable coronary heart disease: findings f...
23123999 - Minimal-access left ventricular assist device explantation.
24970969 - Myocardial infarction in young adults-risk factors and pattern of coronary artery invol...
24927909 - Clinical outcomes with β-blockers for myocardial infarction a meta-analysis of randomi...
23555019 - Cyp2c19 phenotype, stent thrombosis, myocardial infarction, and mortality in patients w...
2911199 - Postinfarction ventricular septal defect. an efficacious technique for early surgical r...
1909199 - N-nitro l-arginine causes coronary vasoconstriction and inhibits endothelium-dependent ...
24621939 - Long-term trajectory of two unique cardiac biomarkers and subsequent left ventricular s...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-26
Journal Detail:
Title:  Neuroscience letters     Volume:  -     ISSN:  1872-7972     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-6-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011. Published by Elsevier Ireland Ltd.
Department of Neurology, Graduate School of Medicine, Kyoto University, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Phase-amplitude coupling between theta and gamma oscillations during nociception in rat electroencep...
Next Document:  Differential expression of miRNA-146a-regulated inflammatory genes in human primary neural, astrogli...