| Waterborne versus Dietary Zinc Accumulation and Toxicity in Daphnia magna: a Synchrotron Radiation Based X-ray Fluorescence Imaging Approach. | |
| | |
MedLine Citation:
|
PMID: 22208159 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Recent studies have suggested that exposure of the freshwater invertebrate Daphnia magna to dietary Zn may selectively affect reproduction without an associated increase of whole body bioaccumulation of Zn. The aim of the current research was therefore to investigate the hypothesis that dietary Zn toxicity is the result of selective accumulation in tissues that are directly involved in reproduction. Since under field conditions simultaneous exposure to both waterborne and dietary Zn is likely to occur, it was also tested if accumulation and toxicity under combined waterborne and dietary Zn exposure is the result of interactive effects. To this purpose, D. magna was exposed during a 16-day reproduction assay to Zn following a 5 × 2 factorial design, comprising five waterborne concentrations (12, 65, 137, 207, and 281 μg Zn/L) and two dietary Zn levels (49.6 and 495.9 μg Zn/g dry wt.). Tissue-specific Zn distribution was quantified by synchrotron radiation based confocal X-ray fluorescence (XRF). It was observed that the occurrence of reproductive inhibition due to increasing waterborne Zn exposure (from 65 μg/L to 281 μg/L) was accompanied by a relative increase of the Zn burdens which was similar in all tissues considered (i.e., the carapax, eggs, thoracic appendages with gills and the cluster comprising gut epithelium, storage cells and ovaries). In contrast, the impairment of reproduction during dietary Zn exposure was accompanied by a clearly discernible Zn accumulation in the eggs only (at 65 μg/L of waterborne Zn). During simultaneous exposure, bioaccumulation and toxicity were the result of interaction, which implies that the tissue-specific bioaccumulation and toxicity following dietary Zn exposure are dependent on the Zn concentration in the water. Our findings emphasize that (i) effects of dietary Zn exposure should preferably not be investigated in isolation from waterborne Zn exposure, and that (ii) XRF enabled us to provide possible links between tissue-specific bioaccumulation and reproductive effects of Zn. |
| | |
Authors:
|
R Evens; K A C De Schamphelaere; B De Samber; G Silversmit; T Schoonjans; B Vekemans; L Balcaen; F Vanhaecke; I Szaloki; K Rickers; G Falkenberg; L Vincze; C R Janssen |
Related Documents
:
|
18289619 - Dieting and food choice in grocery shopping. 15933399 - Body weight changes in elderly psychogeriatric nursing home residents. 22236199 - Tissue-specific differences in inflammatory infiltrate and matrix metalloproteinase exp... 3575869 - Valorization of rapeseed meal. 3. effects of glucosinolate content on food intake, weig... 22262159 - Tissue-specific responses of lipoprotein lipase to dietary macronutrient composition as... 21562909 - In vitro screening for antihyperlipidemic activities in foodstuffs by evaluating lipopr... 6322799 - Effect of maternal ethanol ingestion during pregnancy and lactation on the structure an... 19520739 - Stimulation of incretin secretion by dietary lipid: is it dose dependent? 22111629 - Effects of growth and dietary crude protein level until first insemination on milk prod... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-28 |
Journal Detail:
|
Title: Environmental science & technology Volume: - ISSN: 1520-5851 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2012-1-2 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0213155 Medline TA: Environ Sci Technol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Laboratory of Environmental Toxicology, Ghent University , Ghent, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Implants with external hexagon and conical implant-abutment connections: an in vitro study of the ba...
Next Document: A possible role to nitric oxide in the anti-inflammatory effects of amitriptyline.