Document Detail


Water and electrolyte absorption and secretion in the small intestine.
MedLine Citation:
PMID:  17023929     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The use of gene-knockout mice permits an increased insight into the role of specific transport proteins and membrane receptors in epithelial water and electrolyte transport. Data on the secondary coupling of water transport to Na-glucose cotransport and the mechanism of action of a number of prosecretory and proabsorptive enteric neurotransmitters are reviewed. Nitric oxide and some experimental treatments with therapeutic potential for cholera toxin-induced water and electrolyte secretion are discussed. A putative role of uroguanylin in intestinal bicarbonate secretion is explored.
Authors:
J L Turvill; M J Farthing
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in gastroenterology     Volume:  15     ISSN:  0267-1379     ISO Abbreviation:  Curr. Opin. Gastroenterol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  2006-10-06     Completed Date:  2007-07-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506887     Medline TA:  Curr Opin Gastroenterol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  108-12     Citation Subset:  -    
Affiliation:
Institution Digestive Diseases Research Centre, St. Bartholomew's and The Royal London School of Medicine and Dentistry, Start 1, 2, Newark Street, London E1 2AD, UK.
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