Document Detail

Warfarin and uric acid after myocardial infarction.
MedLine Citation:
PMID:  3544688     Owner:  NLM     Status:  MEDLINE    
In order to assess the influence of warfarin on serum urate concentration, changes in serum urate were studied in 50 patients after myocardial infarction. The patients studied were part of a prospective, randomized placebo-controlled study of warfarin after myocardial infarction. Twenty-three of the patients were treated with warfarin and 27 received placebo. The mean uric acid level fell in both groups during an average of 10 months (range 6-20 months), the reduction being of the same order of magnitude in either group. This implies that warfarin, in contrast to some other oral anticoagulants, does not exert any uric acid lowering effect.
P Smith; H Arnesen
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  220     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1986  
Date Detail:
Created Date:  1987-03-05     Completed Date:  1987-03-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  407-10     Citation Subset:  IM    
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MeSH Terms
Clinical Trials as Topic
Middle Aged
Myocardial Infarction / blood,  drug therapy*
Prospective Studies
Random Allocation
Time Factors
Uric Acid / blood*
Warfarin / therapeutic use*
Reg. No./Substance:
69-93-2/Uric Acid; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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