Document Detail

Warfarin--topical salicylate interactions: case reports.
MedLine Citation:
PMID:  8926909     Owner:  NLM     Status:  MEDLINE    
This paper deals with two patients on warfarin in whom the use of topical methylsalicylate preparations led to clinically significant bleeding problems. The first patient required fresh frozen plasma to tide over the crisis while the second patient recovered spontaneously on stopping the warfarin temporarily. The possible mechanisms by which salicylates potentiate the anticoagulant effect of warfarin are briefly outlined.
M Ramanathan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Medical journal of Malaysia     Volume:  50     ISSN:  0300-5283     ISO Abbreviation:  Med. J. Malaysia     Publication Date:  1995 Sep 
Date Detail:
Created Date:  1996-11-07     Completed Date:  1996-11-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361547     Medline TA:  Med J Malaysia     Country:  MALAYSIA    
Other Details:
Languages:  eng     Pagination:  278-9     Citation Subset:  IM    
Department of Medicine, Taiping Hospital, Perak.
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MeSH Terms
Anti-Inflammatory Agents / adverse effects*
Anticoagulants / adverse effects*
Drug Interactions
Gingiva / blood supply
Hematoma / chemically induced
Hemorrhage / chemically induced*
Leg / blood supply
Middle Aged
Salicylates / adverse effects*
Warfarin / adverse effects*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Anticoagulants; 0/Salicylates; 0/Steroids; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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