Document Detail

Warfarin-induced Leukocytoclastic Vasculitis: A Case Report and Review of Literature.
MedLine Citation:
PMID:  22449668     Owner:  NLM     Status:  In-Data-Review    
Warfarin is widely prescribed for patients with atrial fibrillation. In addition to unexpected bleeding, allergic skin reaction is one of its uncommon adverse effects. We herein report an 89-year-old man who, after taking warfarin for 4 years, suffered extensive skin eruptions. The skin biopsy disclosed leukocytoclastic vasculitis. The causal relationship between skin lesions and warfarin was confirmed after re-challenge of warfarin. A literature review revealed only 13 such cases reported from 1980 to 2011. Clinicians should be aware of this potential adverse effect of warfarin.
Chien-Yi Hsu; Wei-Sheng Chen; Shih-Hsien Sung
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Publication Detail:
Type:  Journal Article     Date:  2012-03-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  51     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2012  
Date Detail:
Created Date:  2012-03-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  601-6     Citation Subset:  IM    
Division of Cardiology, Taipei Veterans General Hospital, Taiwan.
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