Document Detail


Warfarin in Heart Failure.
MedLine Citation:
PMID:  22551103     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Despite major advances in the management of heart failure with angiotensin-converting-enzyme inhibitors, beta-blockers, and resynchronization therapy, there are more than 1 million hospitalizations for heart failure in the United States each year, and mortality remains high.(1) As compared with the general population, patients with heart failure have an increased risk of stroke and of systemic thromboembolic events, which are believed to arise from within the heart as a result of left ventricular stasis, endocardial dysfunction, and a systemic hypercoagulable state.(2) Heart failure is a risk factor for atrial fibrillation, which, even if asymptomatic, further increases the risk of stroke.(3) Consequently, . . .
Authors:
John W Eikelboom; Stuart J Connolly
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-2
Journal Detail:
Title:  The New England journal of medicine     Volume:  -     ISSN:  1533-4406     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-5-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
From the Department of Medicine, McMaster University, Hamilton, ON, Canada.
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