Document Detail


Warfarin anticoagulation in the horse.
MedLine Citation:
PMID:  7440316     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The hematologic and clinical effects of anticoagulation with warfarin were documented in 4 horses. All of the animals had thrombophlebitis (external jugular vein). Measures of coagulation were monitored, with a prothrombin time of 1.5 to 2.5 x base-line value being used as the effective range of anticoagulation. Recanalization was achieved in 2 of 4 cases. Hemorrhage, both subcutaneous and through a surgical incision, was a complication. Vitamin K1, an antidote to warfarin toxicosis, was administered intravenously to reverse anticoagulation and to control hemorrhage.
Authors:
E A Scott; T D Byars; A M Lamar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the American Veterinary Medical Association     Volume:  177     ISSN:  0003-1488     ISO Abbreviation:  J. Am. Vet. Med. Assoc.     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-02-19     Completed Date:  1981-02-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7503067     Medline TA:  J Am Vet Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1146-51     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blood Coagulation / drug effects*
Blood Coagulation Factors
Female
Hemorrhage / etiology,  veterinary
Horses*
Male
Vitamin K / pharmacology
Warfarin / adverse effects,  pharmacology*
Chemical
Reg. No./Substance:
0/Blood Coagulation Factors; 12001-79-5/Vitamin K; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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