Document Detail


Waning immunity to varicella in infants of human immunodeficiency virus-seropositive and -seronegative mothers.
MedLine Citation:
PMID:  21412180     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immunity to varicella in HIV-exposed and -unexposed infants born to unvaccinated mothers, acquiring protective antibodies at birth declined to nonprotective (<1:8) levels by 5 months of age. Therefore, infants become susceptible to varicella before 12 months, which is the recommended time for varicella immunizations in the United States. Vaccination of susceptible HIV-seronegative women in the postpartum period may be important to consider.
Authors:
Shahana A Choudhury; Gwinnett Ladson; Edward R Hills; Frank Hatcher
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  30     ISSN:  1532-0987     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-18     Completed Date:  2011-12-07     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  799-801     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Meharry Medical College, Nashville, TN, USA. schoudhury@mmc.edu
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Viral / immunology
CD4 Lymphocyte Count
Chickenpox / immunology*,  virology
Female
HIV / genetics,  immunology
HIV Infections / immunology,  virology
HIV Seronegativity / immunology*
HIV Seropositivity / immunology*,  virology
Herpesvirus 3, Human / immunology*
Humans
Infant
Infant, Newborn
Pregnancy
Pregnancy Complications, Infectious / immunology,  virology
Grant Support
ID/Acronym/Agency:
P20 RR011792-04/RR/NCRR NIH HHS; P20RR11792/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Antibodies, Viral
Comments/Corrections

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