| Walter Gaskell and the understanding of atrioventricular conduction and block. | |
| | |
MedLine Citation:
|
PMID: 12020482 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Walter Holbrook Gaskell was a nineteenth-century British physiologist whose investigations from 1874 until 1889 became central to our current understanding of cardiac physiology. His many cardiac contributions include the following: 1) the recognition of certain inherent properties of cardiac muscle; 2) the experimental proof that led to the acceptance of the myogenic theory of the origin of the heartbeat; 3) the mapping of the anatomy of the sympathetic nervous system; 4) the understanding of the dual autonomic control of the heart; 5) the discovery of the vasodilating effect of sympathetic stimulation on blood flow through skeletal muscle arteries; and 6) the introduction of the concept of heart block. Gaskell's elucidation of the sequence of cardiac contraction and atrioventricular block and his concepts of rhythmicity, excitability, contractility, conductivity and tonicity provided the physiologic explanation necessary for the future understanding of cardiac rhythm disturbances. |
| | |
Authors:
|
Mark E Silverman; Charles B Upshaw |
Publication Detail:
|
Type: Biography; Historical Article; Journal Article; Portraits |
Journal Detail:
|
Title: Journal of the American College of Cardiology Volume: 39 ISSN: 0735-1097 ISO Abbreviation: J. Am. Coll. Cardiol. Publication Date: 2002 May |
Date Detail:
|
Created Date: 2002-05-21 Completed Date: 2002-06-06 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 8301365 Medline TA: J Am Coll Cardiol Country: United States |
Other Details:
|
Languages: eng Pagination: 1574-80 Citation Subset: AIM; IM |
Affiliation:
|
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA. marksil@attbi.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Electrocardiography / history* England Heart / physiology Heart Block / history*, physiopathology History, 19th Century History, 20th Century Humans Physiology / history |
| Personal Name Subject | |
Personal Name Subject:
|
Walter Gaskell |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Statins and chronic heart failure: do we need a large-scale outcome trial?
Next Document: A prospective, multicenter, randomized trial of percutaneous transmyocardial laser revascularization...