| Walking for prevention of cardiovascular disease in men and women: a systematic review of observational studies. | |
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MedLine Citation:
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PMID: 19207874 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In this systematic review, walking (a generally accessible activity for a largely sedentary population) was assessed as a preventive risk factor for development of fatal and non-fatal cardiovascular disease (CVD). PubMed, CINHAL and reference list searches identified 21 peer-reviewed publications examining walking in relation to CVD; studies assessing active transportation were excluded. Generally, there were dose-dependent reductions in CVD risk with higher walking duration, distance, energy expenditure and pace. Associations appeared to be stronger for ischaemic stroke than other CVD outcomes such as coronary heart disease or haemorrhagic stroke. Adjustment for clinical CVD risk factors, obesity or other types of physical activity generally attenuated but did not eliminate associations. Because functional status may be an important determinant of walking behaviour in adults, potential bias due to pre-existing illness is of concern in all studies reviewed, particularly in case-control studies which ascertain walking retrospectively and yielded the strongest associations. Study findings were consistent with current physical activity recommendations, but there is a need for improvements in measurement of walking and other CVD risk factors, more thorough control for pre-existing illness, examination of mediating or moderating conditions such as obesity and other analytical issues. |
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Authors:
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J Boone-Heinonen; K R Evenson; D R Taber; P Gordon-Larsen |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2008-12-10 |
Journal Detail:
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Title: Obesity reviews : an official journal of the International Association for the Study of Obesity Volume: 10 ISSN: 1467-789X ISO Abbreviation: Obes Rev Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-02-27 Completed Date: 2009-06-19 Revised Date: 2011-04-07 |
Medline Journal Info:
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Nlm Unique ID: 100897395 Medline TA: Obes Rev Country: England |
Other Details:
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Languages: eng Pagination: 204-17 Citation Subset: IM |
Affiliation:
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Department of Nutrition, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516-3997, USA. boonej@unc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiovascular Diseases
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prevention & control* Female Humans Male Research Design Time Factors Walking* |
| Grant Support | |
ID/Acronym/Agency:
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K01 HD044263-05/HD/NICHD NIH HHS; K01-HD044263/HD/NICHD NIH HHS; R01 CA109831/CA/NCI NIH HHS; R01 CA109831-05/CA/NCI NIH HHS; R01 CA121152-04/CA/NCI NIH HHS; R01 HD057194-04/HD/NICHD NIH HHS; R01-CA12115/CA/NCI NIH HHS |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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