| Walking, lipids, and lipoproteins: a meta-analysis of randomized controlled trials. | |
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MedLine Citation:
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PMID: 15066369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The purpose of this study was to use the meta-analytic approach to examine the effects of walking on lipids and lipoproteins in adults. METHODS: Randomized controlled trials that examined the effects of walking on total cholesterol (TC), high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), the ratio of TC/HDL, and triglycerides (TG) in adults ages 18 years and older were retrieved via computerized literature searches, cross-referencing, hand-searching, and expert review of our reference list. RESULTS: Twenty-five studies that included 1,176 subjects (692 walkers, 484 controls) and up to 33 outcomes were available for pooling. Using random-effects modeling, statistically significant, walking-induced decreases of 5% and 6% were observed for LDL-C and TC/HDL-C (LDL-C, mean +/- SE, -5.5 +/- 2.2 mg/dL, 95% CI, -9.9 to -1.2 mg/dL; TC/HDL-C, mean +/- SE, -0.3 +/- 0.1, 95% CI, -0.6 to -0.1). No statistically significant changes were observed for TC, HDL, or TG (P > 0.05), although changes were in the direction of benefit. No statistically significant changes occurred in body composition (P > 0.05). CONCLUSIONS: Walking reduces LDL-C and TC/HDL-C in adults independent of changes in body composition. |
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Authors:
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George A Kelley; Kristi S Kelley; Zung Vu Tran |
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Publication Detail:
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Type: Journal Article; Meta-Analysis; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Preventive medicine Volume: 38 ISSN: 0091-7435 ISO Abbreviation: Prev Med Publication Date: 2004 May |
Date Detail:
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Created Date: 2004-04-06 Completed Date: 2004-07-23 Revised Date: 2008-11-20 |
Medline Journal Info:
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Nlm Unique ID: 0322116 Medline TA: Prev Med Country: United States |
Other Details:
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Languages: eng Pagination: 651-61 Citation Subset: IM |
Affiliation:
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Department of Community Medicine, School of Medicine, West Virginia University, Morgantown, WV 26506-9190, USA. gkelley@hsc.wvu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cholesterol / blood*, classification Female Humans Lipoproteins / blood*, classification Male Middle Aged Randomized Controlled Trials as Topic* Triglycerides / blood* Walking* |
| Grant Support | |
ID/Acronym/Agency:
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R01 HL069802-03/HL/NHLBI NIH HHS; R01-HL069802/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Lipoproteins; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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