Document Detail

Walking for exercise--does three times per week influence risk factors in type 2 diabetes?
MedLine Citation:
PMID:  16005099     Owner:  NLM     Status:  MEDLINE    
In order to assess the effects of regular walking on metabolic control and cardiovascular risk factors in type 2 diabetes 26 patients from one primary care clinic, aged 60.0+/-7.3 years, participated in a walking program during 4 months. Prescribed exercise was walking for 45-60 min three times weekly. A control group of 26 patients from a neighboring primary care clinic, aged 59.3+/-6.2 years, received no exercise instructions. Thus, randomization was not performed. There were no improvements of blood pressure, body mass index, physical fitness, glycated hemoglobin A1c, fasting plasma glucose or insulin by intention-to-treat analysis. Seventeen patients in the intervention group increased their physical activity and improved systolic blood pressure; -7.6 mmHg (-15 to -0.2), diastolic blood pressure; -4.3 mmHg (-7.4 to -1.2), body mass index; -0.6 kg/m2 (-1.1 to -0.1) and total plasma cholesterol; -0.6 mmol/l (-0.9 to -0.3), (mean difference, with 95% CI). We could observe no effects on glucose metabolism in either group. Our results suggest that an increase of regular physical activity equivalent to 45 min of walking 3 days/week may suffice to improve systolic and diastolic blood pressure, lipid metabolism and BMI in patients with type 2 diabetes.
Tomas Fritz; Per Wändell; Hans Aberg; Peter Engfeldt
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Publication Detail:
Type:  Journal Article     Date:  2005-07-06
Journal Detail:
Title:  Diabetes research and clinical practice     Volume:  71     ISSN:  0168-8227     ISO Abbreviation:  Diabetes Res. Clin. Pract.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2005-12-26     Completed Date:  2006-02-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8508335     Medline TA:  Diabetes Res Clin Pract     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  21-7     Citation Subset:  IM    
Center of Family Medicine, Karolinska Institutet, Alfred Nobels Allé 12, SE 141 83 Huddinge, Sweden.
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MeSH Terms
Blood Glucose / metabolism
Blood Pressure / physiology*
Body Mass Index*
Cholesterol / blood*
Diabetes Mellitus, Type 2 / metabolism*,  prevention & control
Energy Metabolism
Exercise Therapy / methods*
Heart Rate
Hemoglobin A, Glycosylated / metabolism
Insulin / blood
Middle Aged
Risk Factors
Walking / physiology*
Reg. No./Substance:
0/Blood Glucose; 0/Hemoglobin A, Glycosylated; 11061-68-0/Insulin; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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