Document Detail


Waist circumference, but not body mass index, is a predictor of ventricular remodeling after anterior myocardial infarction.
MedLine Citation:
PMID:  22959633     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: The impact of obesity on ventricular remodeling after myocardial infarction (MI) is still poorly understood. Therefore, the aim of this study was to evaluate the role of waist circumference (WC) and body mass index as predictors of cardiac remodeling in patients after an anterior MI. METHODS: Eighty-three consecutive patients with anterior MI were prospectively evaluated. Clinical characteristics and echocardiographic data were analyzed at admission and at a 6-mo follow-up. Ventricular remodeling was defined as a 10% increase in left ventricular end-systolic or end-diastolic diameter at the 6-mo follow-up. RESULTS: In our study, 83 consecutive patients were evaluated (72% men). Ventricular remodeling was present in 31% of the patients (77% men). Patients with remodeling had higher creatine phosphokinase and creatine phosphokinase-MB peak values, a higher resting heart rate, a larger left atrial diameter, and a larger interventricular septum diastolic thickness. In addition, patients with remodeling had lower peak velocity of early ventricular filling deceleration time and ejection fraction. Patients with remodeling presented higher WC values (with remodeling, 99.2 ± 10.4 cm; without remodeling, 93.9 ± 10.8 cm, P = 0.04), but there were no differences in the body mass index values. In the logistic regression analysis, WC, adjusted by age, gender, ejection fraction, and creatine phosphokinase levels, was an independent predictor of left ventricular remodeling (odds ratio 1.067, 95% confidence interval 1.001-1.129, P = 0.02). CONCLUSION: Waist circumference, but not body mass index, is a predictor of ventricular remodeling after an anterior MI. Therefore, the WC of these patients should be measured in clinical practice.
Authors:
Ana Lucia Cogni; Elaine Farah; Marcos F Minicucci; Paula S Azevedo; Katashi Okoshi; Beatriz B Matsubara; Silméia G Zanati; Sergio A R Paiva; Leonardo A M Zornoff
Related Documents :
12189323 - Selective treatment for heart failure: the future beckons?
16041173 - Prediction of prognosis in the um-x7.1 hamster model of congestive heart failure using ...
8225903 - Consideration of measurements of myocardial blood flow with positron-emission tomography.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-6
Journal Detail:
Title:  Nutrition (Burbank, Los Angeles County, Calif.)     Volume:  -     ISSN:  1873-1244     ISO Abbreviation:  Nutrition     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8802712     Medline TA:  Nutrition     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Internal Medicine Department, Botucatu Medical School, São Paulo State University, Botucatu, São Paulo, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Nelumbo nucifera leaf extract inhibits neointimal hyperplasia through modulation of smooth muscle ce...
Next Document:  Increased plasma availability of L-arginine in the postprandial period decreases the postprandial li...