Document Detail

Waist circumference, BMI, and lung function in 8-year-old children: The PIAMA birth cohort study.
MedLine Citation:
PMID:  23143885     Owner:  NLM     Status:  Publisher    
BACKGROUND: Body mass index (BMI) and waist circumference (WC) may be associated with lung function in children, as observed in adults. METHODS: Height, weight, waist circumference, and lung function (FVC and FEV(1) ) were measured during a medical examination in 1,058 eight-year-old children participating in the Prevention and Incidence of Asthma and Mite Allergy (PIAMA) birth cohort study. RESULTS: After adjusting for height, age and other potential confounders large WC or high BMI (>90th percentile) were not associated with forced expiratory volume in 1 sec (FEV(1) ) or forced vital capacity (FVC). In girls only, large WC was, independently of BMI, associated with 3.5% (95% confidence interval (CI): -6.4, -0.6) lower FEV(1) /FVC ratio in the model including WC and BMI. Girls with low BMI (<10th percentile) had 4.6% lower FEV(1) (95% CI: -8.4, -0.6) and 5.1% lower FVC (95% CI: -8.8, -1.2) than girls with normal BMI. In boys, we did not observe associations between low or high BMI and lung function independent of WC, or between small or large WC and lung function after adjustment for BMI. CONCLUSION: At 8 years of age, a high BMI or large WC are not yet associated with FEV(1) and FVC, indicating that this association may change over the course of life from childhood to adulthood. Pediatr Pulmonol. © 2012 Wiley Periodicals, Inc.
Marga B M Bekkers; Alet H Wijga; Johan C de Jongste; Marjan Kerkhof; Dirkje Postma; Ulrike Gehring; Henriëtte A Smit; Bert Brunekreef
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-9
Journal Detail:
Title:  Pediatric pulmonology     Volume:  -     ISSN:  1099-0496     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Wiley Periodicals, Inc.
Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, The Netherlands; Centre for Prevention and Health Services Research, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands.
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