Document Detail


WNT signaling and lymphocyte development.
MedLine Citation:
PMID:  11983149     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Developmental studies in model organisms have revealed that cell fate decisions are governed by only a handful of highly conserved signal transduction cascades. Recent data indicate that at least two of these, the Wnt and the Notch cascades, have been recruited by the vertebrate immune system to control early lymphopoiesis.
Authors:
Marc van de Wetering; Wim de Lau; Hans Clevers
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Cell     Volume:  109 Suppl     ISSN:  0092-8674     ISO Abbreviation:  Cell     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-05-01     Completed Date:  2002-05-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  S13-9     Citation Subset:  IM    
Affiliation:
Department of Immunology, UMC Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Differentiation*
Cell Lineage
DNA-Binding Proteins / genetics,  metabolism
Humans
Lymphocytes / cytology*,  metabolism*
Lymphoid Enhancer-Binding Factor 1
Mice
Mice, Knockout
Proto-Oncogene Proteins / metabolism*
Signal Transduction*
Thymus Gland / cytology,  metabolism
Transcription Factors / genetics,  metabolism
Wnt Proteins
Zebrafish Proteins*
Chemical
Reg. No./Substance:
0/DNA-Binding Proteins; 0/Lymphoid Enhancer-Binding Factor 1; 0/Proto-Oncogene Proteins; 0/Transcription Factors; 0/Wnt Proteins; 0/Zebrafish Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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