| Vulvar vestibulitis syndrome: an often unrecognized cause of dyspareunia. | |
| | |
MedLine Citation:
|
PMID: 10099756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vulvar vestibulitis syndrome (VVS) is an easily identifiable cause of entry dyspareunia. The aetiology is unknown although there is a strong association with Candida infection. The condition represents a focal area of hyperaesthesia within the vulvar vestibule. A management protocol for patients with this condition is presented; 230 patients with VVS were managed and followed-up over a 5-year period. Spontaneous resolution or improvement occurred in 21% of patients following initial explanation and use of simple local measures. In 21%, there were positive Candida cultures and long-term antifungal therapy resulted in a 71% cure. In Candida-negative patients, low-dose amitriptyline was used (up to 75 mg daily) with a 60% positive response rate. Carbamazepine was of little benefit (13% response). Surgical vestibulectomy was offered when conservative measures failed and this was performed in 22 patients (10%) with a beneficial result in 20 patients (91%). |
| | |
Authors:
|
R Pagano |
Related Documents
:
|
11014766 - Identification of enteric pathogens in hiv-positive patients with diarrhoea in northern... 3052346 - The intravenous pyelogram in acute pyelonephritis. 1744306 - Antibiotic levels in bronchial tree and in serum during selective digestive decontamina... 10519696 - Otogenic lateral sinus thrombosis in children. 20974326 - Immunologic response to fungus is not universally associated with chronic rhinosinusitis. 2012726 - Ct of liver steatosis after subtotal pancreatectomy. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The Australian & New Zealand journal of obstetrics & gynaecology Volume: 39 ISSN: 0004-8666 ISO Abbreviation: Aust N Z J Obstet Gynaecol Publication Date: 1999 Feb |
Date Detail:
|
Created Date: 1999-05-20 Completed Date: 1999-05-20 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0001027 Medline TA: Aust N Z J Obstet Gynaecol Country: AUSTRALIA |
Other Details:
|
Languages: eng Pagination: 79-83 Citation Subset: IM |
Affiliation:
|
Vulvar Disorders Clinic, Royal Women's Hospital, Melbourne, Victoria. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Aged Amitriptyline / therapeutic use Analgesics, Non-Narcotic / therapeutic use Antidepressive Agents, Tricyclic / therapeutic use Antifungal Agents / therapeutic use Candidiasis, Vulvovaginal / complications*, diagnosis, drug therapy* Carbamazepine / therapeutic use Dyspareunia / etiology* Female Follow-Up Studies Humans Hyperesthesia / complications*, diagnosis, drug therapy* Ketoconazole / therapeutic use Middle Aged Prospective Studies Risk Factors Syndrome Treatment Outcome Vulvitis / complications*, diagnosis, drug therapy* |
| Chemical | |
Reg. No./Substance:
|
0/Analgesics, Non-Narcotic; 0/Antidepressive Agents, Tricyclic; 0/Antifungal Agents; 298-46-4/Carbamazepine; 50-48-6/Amitriptyline; 65277-42-1/Ketoconazole |
| Comments/Corrections | |
Comment In:
|
Aust N Z J Obstet Gynaecol. 1999 Aug;39(3):397
[PMID:
10554969
]
Aust N Z J Obstet Gynaecol. 2000 Feb;40(1):108-9 [PMID: 10870796 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Hilus cell tumour of the ovary in a virilized, premenopausal woman. Case report and review of hypera...
Next Document: Contribution of the assisted reproductive technologies to fertility in males suffering spinal cord i...