Document Detail

Vulvar skin atrophy induced by topical glucocorticoids.
MedLine Citation:
PMID:  22594868     Owner:  NLM     Status:  MEDLINE    
Steroid-induced skin atrophy is the most frequent and perhaps most important cutaneous side effect of topical glucocorticoid therapy. To date, it has not been described in vulvar skin. A patient presented with significant vulvar skin atrophy following prolonged steroid application to treat vulvar dermatitis. The extensive atrophy in the perineum resulted in secondary "webbing" and partial obstruction of the genital hiatus and superimposed dyspareunia. Prolonged use of topical steroids may result in atrophic changes in vulvar skin. Further research in clinical correlates of steroid-induced atrophy in the vulvar region is warranted.
Elisabeth Johnson; Pamela Groben; Alisa Eanes; Priya Iyer; Joseph Ugoeke; Denniz Zolnoun
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of midwifery & women's health     Volume:  57     ISSN:  1542-2011     ISO Abbreviation:  J Midwifery Womens Health     Publication Date:    2012 May-Jun
Date Detail:
Created Date:  2012-05-18     Completed Date:  2012-07-20     Revised Date:  2014-02-04    
Medline Journal Info:
Nlm Unique ID:  100909407     Medline TA:  J Midwifery Womens Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  296-9     Citation Subset:  IM; N    
Copyright Information:
© 2012 by the American College of Nurse-Midwives.
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MeSH Terms
Administration, Cutaneous
Atrophy / chemically induced
Dermatitis, Atopic / drug therapy
Estrogens / therapeutic use
Glucocorticoids / administration & dosage,  adverse effects*,  therapeutic use
Middle Aged
Vulva / pathology*
Vulvar Diseases / chemically induced*,  drug therapy
Grant Support
K23 HD053631-04/HD/NICHD NIH HHS
Reg. No./Substance:
0/Estrogens; 0/Glucocorticoids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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