Document Detail

Vulnerable plaque imaging-current techniques.
MedLine Citation:
PMID:  20559964     Owner:  NLM     Status:  MEDLINE    
Tremendous progress has been made over the past 30 years in the management of plaque rupture and acute coronary thrombosis. With the advent of new interventional cardiac techniques and concomitant advances in medical therapy, there has been a steady decline in cardiovascular mortality. Acute coronary syndromes, especially ST elevation myocardial infarction, still occur frequently and are associated with significant morbidity and mortality. As these events typically occur in lesions without severe pre-existing stenosis, interest has increased in identifying these "vulnerable plaques" and ultimately preventing myocardial infarction. Recently, several new invasive and non-invasive modalities have been developed to identify and better characterize vulnerable plaque. This review will cover the pathobiology of vulnerable plaque, current invasive and non-invasive imaging techniques, tissue characterization, and future applications of this exciting technology.
K Chad Hilty; Daniel H Steinberg
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Publication Detail:
Type:  Journal Article; Review     Date:  2009-01-14
Journal Detail:
Title:  Journal of cardiovascular translational research     Volume:  2     ISSN:  1937-5395     ISO Abbreviation:  J Cardiovasc Transl Res     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2010-06-18     Completed Date:  2010-10-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101468585     Medline TA:  J Cardiovasc Transl Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9-18     Citation Subset:  IM    
Cardiology Division, Medical University of South Carolina, 25 Courtenay Drive, ART 7058, Box 592, Charleston, SC 29425, USA.
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MeSH Terms
Acute Coronary Syndrome / complications,  diagnosis*,  therapy
Coronary Angiography
Diagnostic Imaging* / methods
Disease Progression
Elasticity Imaging Techniques
Magnetic Resonance Imaging
Myocardial Infarction / diagnosis*,  etiology,  prevention & control
Predictive Value of Tests
Severity of Illness Index
Spectroscopy, Near-Infrared
Tomography, Emission-Computed, Single-Photon
Tomography, Optical Coherence
Tomography, X-Ray Computed
Ultrasonography, Interventional

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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