| Volume reflex in diabetes. | |
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MedLine Citation:
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PMID: 9217876 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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After examining various components of the volume reflex in different models of diabetic rats, it is clear that the neural component of the volume reflex is altered in the early stage of diabetes. Nevertheless, the mechanisms involved in the neural component need to be examined further in diabetes. In terms of the humoral component of the effector limb of the volume reflex, the actions of ANF within the kidney appear to contribute to the altered volume reflex in diabetes. Results of our preliminary studies suggest that intrarenal factors may also contribute to the blunted renal excretory responses to acute VE in early diabetes. Finally, the present review has outlined the major abnormalities in the volume reflex in diabetes and the gaps in our knowledge of the various components of the volume reflex in diabetes. |
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Authors:
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K P Patel |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Cardiovascular research Volume: 34 ISSN: 0008-6363 ISO Abbreviation: Cardiovasc. Res. Publication Date: 1997 Apr |
Date Detail:
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Created Date: 1997-08-11 Completed Date: 1997-08-11 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0077427 Medline TA: Cardiovasc Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 81-90 Citation Subset: IM |
Affiliation:
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Department of Physiology and Biophysics, University of Nebraska Medical Center, Omaha 68198-4575, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Autonomic Nervous System / physiopathology* Diabetes Mellitus / physiopathology* Humans Kidney / physiopathology Rats Reflex* Water-Electrolyte Balance* |
| Grant Support | |
ID/Acronym/Agency:
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R01-HL 48023/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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