Document Detail

Volume optimization in surgical patients: wet or dry?
MedLine Citation:
PMID:  18274244     Owner:  NLM     Status:  MEDLINE    
Perioperative fluid therapy remains the subject of active controversy. Indeed, clinical trials investigating the effects of fluid administration on outcome in surgical patients report controversial results. Critical review of these trials reveals that current standard fluid therapy is not at all evidence-based. Although it is evident that fluid overload should be avoided, replacement of fluid lost clearly improves outcome. The debate "Wet or Dry" is not a real one. Fluids should be administered in the perioperative period through a goal-directed approach taking into account patients characteristics and surgical-related events, and not through a "recipe book" approach. The type of fluid to be administered should depend on the specific space that needs to be restored (intracellular, extracellular or intravascular) and on the pharmacokinetic properties of the different solutions.
P Van der Linden
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  58     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  2007  
Date Detail:
Created Date:  2008-02-15     Completed Date:  2008-03-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  245-50     Citation Subset:  IM    
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MeSH Terms
Blood Substitutes / administration & dosage,  chemistry,  therapeutic use*
Blood Volume / physiology*
Fluid Therapy / adverse effects,  standards*
Guidelines as Topic
Perioperative Care*
Surgical Procedures, Operative
Reg. No./Substance:
0/Blood Substitutes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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