Document Detail

Volume estimation in dialysis patients: The concordance of brain-type natriuretic peptide measurements and bioimpedance values.
MedLine Citation:
PMID:  23362989     Owner:  NLM     Status:  Publisher    
Correct estimation of the dialysis patients' hydration status remains an important clinical challenge. Bioimpedance measurements have been validated by various physiological tests, and the use of brain-type natriuretic peptide (BNP) has been validated by inferior vena cava diameter measurements. This is an observational cohort study that evaluated the correspondence between bioimpedance-measured overhydration percentage (OH%) and BNP. We measured predialysis OH% by bioimpedance apparatus (Body Composition Monitor) and BNP by microparticle enzyme-linked immunoassay in 41 prevalent stable hemodialysis patients, 19 (46%) women, aged 58.9 ± 14.5 years. The cohort's average BNP was 2694 ± 3278 pg/mL and 10 (24.4%) of these 41 patients had BNP < 500 pg/mL (average 260.7 ± 108.5). The OH% was 8.5 ± 7.0% among those with a BNP < 500 pg/mL, while the rest of the population had an OH% of 21.4 ± 8.0%, corresponding to excess volumes of 1.6 ± 1.3 and 4.4 ± 3.8 L, respectively. The OH% vs. BNP relationship was best described by the exponential regression of y = 216.4e(0.097x) , predicting a BNP of 216.4 pg/mL at 0% overhydration status (r 0.61). Receiver-operating curves revealed an area under the curve of 0.885 for BNP when the OH% was set ≥15% of overhydration and an area under the curve of 0.918 for OH% when the BNP was set ≥500 pg/mL for being abnormal. We conclude that in our cohort there was a high degree of correspondence between these two tests with an exponential relationship between the measurements.
Mihály Tapolyai; Mária Faludi; Virág Réti; Zsolt Lengvárszky; Tibor Szarvas; Tibor Fülöp; Gabriella Bekő; Klára Berta
Related Documents :
23098149 - A review of the epidemiological profile of patients with atrial fibrillation and heart ...
6153879 - Immunoreactive myelin basic protein in the cerebrospinal fluid in neurological disorders.
14767719 - Decreased cerebrospinal fluid cgmp levels in patients with amyotrophic lateral sclerosis.
6870369 - Significance of post-cholecystectomy subhepatic fluid collections.
10229129 - Elevated levels of interleukin-12 and interferon-gamma in patients with human t lymphot...
11756619 - Persistent movement disorders following japanese encephalitis.
18499399 - Comparison of ferrous sulfate and ferrous glycinate chelate for the treatment of iron d...
21755729 - Ramipril and risk of hyperkalemia in chronic hemodialysis patients.
11864279 - Aspergillus species isolated from clinical specimens: suggested clinical and microbiolo...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-30
Journal Detail:
Title:  Hemodialysis international. International Symposium on Home Hemodialysis     Volume:  -     ISSN:  1542-4758     ISO Abbreviation:  Hemodial Int     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101093910     Medline TA:  Hemodial Int     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 The Authors. Hemodialysis International © 2013 International Society for Hemodialysis.
Fresenius Medical Care, Semmelweis University, Budapest, Hungary.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Transportin 1 accumulates in FUS inclusions in adult-onset ALS without FUS mutation.
Next Document:  Direct evidence of memory retrieval as a source of difficulty in non-local dependencies in language.