Document Detail

Volume-corrected mitotic index as a prognostic factor in oral squamous cell carcinomas.
MedLine Citation:
PMID:  11120486     Owner:  NLM     Status:  MEDLINE    
In order to predict the prognosis of patients with oral squamous cell carcinomas, volume-corrected mitotic index (M/V index), as well as histopathological and clinical indices were estimated in 50 oral squamous cell carcinoma tumors. Histological malignancy (P = 0.0005), mode of invasion (P = 0.0168) and M/V index (P = 0.0093) showed a significant correlation with survival according to univariate survival analysis. According to multivariate survival analysis (Cox's regression model), the M/V index was the best predictor of the techniques studied of patient prognosis. The M/V index also showed significant correlation with DNA ploidy. The present results suggest that the M/V index is an important prognostic factor for oral carcinoma. Furthermore, the M/V index and DNA ploidy appear to provide similar prognostic information.
Y Imai; T Sasaki; T Fujibayashi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral oncology     Volume:  37     ISSN:  1368-8375     ISO Abbreviation:  Oral Oncol.     Publication Date:  2001 Jan 
Date Detail:
Created Date:  2001-01-26     Completed Date:  2001-12-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9709118     Medline TA:  Oral Oncol     Country:  England    
Other Details:
Languages:  eng     Pagination:  72-6     Citation Subset:  IM    
Department of Oral and Maxillofacial Surgery, Dokkyo University School of Medicine, 880 Kita-kobayashi, Mibu, 321-0293, Tochigi, Japan.
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MeSH Terms
Aged, 80 and over
Analysis of Variance
Carcinoma, Squamous Cell / genetics,  pathology*
Follow-Up Studies
Lymphatic Metastasis
Middle Aged
Mitotic Index*
Mouth Neoplasms / genetics,  pathology*
Survival Rate

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