Document Detail

Voltammetric determination of thiodiglycolic acid in urine.
MedLine Citation:
PMID:  12520453     Owner:  NLM     Status:  MEDLINE    
In urine the level of thiodiglycolic acid (TDGA) is a sensitive indicator of exposure of the human organism to some physiologically active or toxic substances, gases and vapors. The determination of TDGA by use of a voltammetric method based on electroreduction of TDGA in acidic solution at the hanging mercury drop electrode has been developed and practically tested. In order to eliminate the matrix effect of urine, prior to voltammetric measurement the samples are eluted from a small column of PVC powder. The method is simple, low cost, rapid and sensitive, appropriate for the needs of occupational medicine.
Zdenka Dlasková; Tomás Navrátil; Michael Heyrovský; Daniela Pelclová; Ladislav Novotný
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2002-11-06
Journal Detail:
Title:  Analytical and bioanalytical chemistry     Volume:  375     ISSN:  1618-2642     ISO Abbreviation:  Anal Bioanal Chem     Publication Date:  2003 Jan 
Date Detail:
Created Date:  2003-01-09     Completed Date:  2003-04-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101134327     Medline TA:  Anal Bioanal Chem     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  164-8     Citation Subset:  IM    
Department of Occupational Medicine, Toxicological Laboratory, 1st Medical Faculty of Charles University, Na Bojisti 1, 128 00 Prague 2, Czech Republic.
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MeSH Terms
Electrochemistry / instrumentation,  methods*
Polyvinyl Chloride / chemistry
Thioglycolates / urine*
Reg. No./Substance:
0/Thioglycolates; 123-93-3/thiodiacetic acid; 9002-86-2/Polyvinyl Chloride

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