| Voltage controlled nano-injection system for single-cell surgery. | |
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MedLine Citation:
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PMID: 22899383 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Manipulation and analysis of single cells is the next frontier in understanding processes that control the function and fate of cells. Herein we describe a single-cell injection platform based on nanopipettes. The system uses scanning microscopy techniques to detect cell surfaces, and voltage pulses to deliver molecules into individual cells. As a proof of concept, we injected adherent mammalian cells with fluorescent dyes. |
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Authors:
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R Adam Seger; Paolo Actis; Catherine Penfold; Michelle Maalouf; Boaz Vilozny; Nader Pourmand |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-16 |
Journal Detail:
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Title: Nanoscale Volume: - ISSN: 2040-3372 ISO Abbreviation: Nanoscale Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101525249 Medline TA: Nanoscale Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Biomolecular Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA. pourmand@soe.ucsc.edu. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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