Document Detail

Vogt-Koyanagi-Harada syndrome: clinical and instrumental contribution.
MedLine Citation:
PMID:  1955305     Owner:  NLM     Status:  MEDLINE    
Vogt-Koyanagi-Harada syndrome is a rare disease, which probably has a cell-mediated autoimmune pathogenesis, marked by ocular (anterior and/or posterior uveitis), dermatological (poliosis, canities, vitiligo) and neurological (meningo-encephalitis) disorders of variable severity in variable combinations. The clinical pattern in the case reported here showed severe neurological involvement (headache, ataxia and confusional state) followed by anteroposterior uveitis. Instrumental investigations (cerebrospinal fluid, VEPs, BAEPs, EEG, CT and MRI brainscans) confirmed the diagnosis. The response to cortisone therapy was excellent. We emphasize the importance of the neuroradiological investigations, because of their peculiarities, and review the reports of cases with marked meningo-encephalitic impairment, given the dearth of reports in the neurological journals.
F Trebini; A Appiotti; R Bacci; D Daniele; A Inglezis; G Scarzella
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Italian journal of neurological sciences     Volume:  12     ISSN:  0392-0461     ISO Abbreviation:  Ital J Neurol Sci     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1991-12-31     Completed Date:  1991-12-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8006502     Medline TA:  Ital J Neurol Sci     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  479-84     Citation Subset:  IM    
Divisione di Neurologia, Ospedale Mauriziano Umberto I di Torino.
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MeSH Terms
Brain / pathology
Headache / pathology
Magnetic Resonance Imaging
Middle Aged
Tomography, X-Ray Computed
Uveitis / pathology
Uveomeningoencephalitic Syndrome / pathology*

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