| Vitreous proteomics and diabetic retinopathy. | |
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MedLine Citation:
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PMID: 21091014 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Diabetic retinopathy is the major cause of acquired blindness in working-age adults. Studies of the vitreous proteome have provided insights into the etiology of diabetic retinopathy and suggested potential molecular targets for treatments. Further characterization of the protein changes associated with the progression of this disease may suggest additional therapeutic approaches as well as reveal novel factors that may be useful in predicting risk and functional outcomes of interventional therapies. This article provides an overview of the various techniques used for proteomic analysis of the vitreous and details results from various studies evaluating vitreous of diabetic patients using the proteomic approach. |
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Authors:
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Saloni Walia; Allen C Clermont; Ben-Bo Gao; Lloyd Paul Aiello; Edward P Feener |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Seminars in ophthalmology Volume: 25 ISSN: 1744-5205 ISO Abbreviation: Semin Ophthalmol Publication Date: 2010 Sep-Nov |
Date Detail:
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Created Date: 2010-11-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610759 Medline TA: Semin Ophthalmol Country: England |
Other Details:
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Languages: eng Pagination: 289-94 Citation Subset: IM |
Affiliation:
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Joslin Diabetes Center, Boston, MA, USA. |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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DK 36836/DK/NIDDK NIH HHS; EY019029/EY/NEI NIH HHS |
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