Document Detail


Vitreous biopsy in uveitis of unknown cause.
MedLine Citation:
PMID:  7348844     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We employed vitreous biopsy (needle aspiration and pars plana vitrectomy) in eight cases of patients with uveitis of unknown etiology. The results of cytological and culture analysis provided the diagnosis of disseminated histoplasmosis in one patient and ocular reticulum cell sarcoma in another patient. In six patients, no specific, treatable causative agents or conditions were identified. In two of these patients, however, various etiologic agents were ruled out, which provided a basis for excluding certain therapeutic options. Where chronic inflammatory cells were seen in the vitreous, the patients responded satisfactorily to conventional therapy; patients with acute or mixed acute and chronic inflammatory cells did less well. No complications resulted from the biopsy procedure. In cases of uveitis of unknown etiology, vitreous biopsy may provide identification of specific causative agents, as well as information useful for more precise histopathologic grouping of entities in this disease.
Authors:
D M Carroll; R M Franklin
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Retina (Philadelphia, Pa.)     Volume:  1     ISSN:  0275-004X     ISO Abbreviation:  Retina (Philadelphia, Pa.)     Publication Date:  1981  
Date Detail:
Created Date:  1983-02-14     Completed Date:  1983-02-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8309919     Medline TA:  Retina     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  245-51     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Biopsy
Female
Humans
Male
Middle Aged
Uveitis / etiology,  pathology*
Vitreous Body / pathology*
Grant Support
ID/Acronym/Agency:
EY02377/EY/NEI NIH HHS; EY03028/EY/NEI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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